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Glucose concentration in blood is regulated by a complex number of pathways, modulated by a variety of hormones. Glucose levels are normally regulated by insulin and other hormones within narrow limits. Fasting glucose levels, 2-hour post prandial glucose levels, and glucose tolerance tests are useful in the diagnosis of diabetes mellitus. Thyroxine is not involved in glucose homeostasis, but stimulates glycogenolysis and increases the rate of intestinal glucose absorption. These factors may produce glucose intolerance, but patients usually have normal fasting plasma glucose levels. Fasting glucose level of > or = 126 mg/dL or 2-h postprandial glucose level of > or = 200 mg/dL is supportive of the diagnosis of diabetes mellitus.

Specimen Required

SST, Serum. Volume 1 (0.5) mL. Stability: Ambient – 24 Hours, Refrigerated – 72 Hours, Frozen – 2 Months

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